Haematopoietic stem and progenitor cell heterogeneity is inherited from the embryonic endothelium

Definitive haematopoietic stem and progenitor cells (HSPCs) generate erythroid, lymphoid and myeloid lineages. HSPCs are produced in the embryo via transdifferentiation of haemogenic endothelial cells in the aorta–gonad–mesonephros (AGM). HSPCs in the AGM are heterogeneous in differentiation and pro...

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Detalles Bibliográficos
Autores principales: Ghersi, Joey J., Baldissera, Gabriel, Hintzen, Jared, Luff, Stephanie A., Cheng, Siyuan, Xia, Ivan Fan, Sturgeon, Christopher M., Nicoli, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415179/
https://www.ncbi.nlm.nih.gov/pubmed/37460694
http://dx.doi.org/10.1038/s41556-023-01187-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415179/
https://www.ncbi.nlm.nih.gov/pubmed/37460694
http://dx.doi.org/10.1038/s41556-023-01187-9

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