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The Troyer syndrome protein spartin mediates selective autophagy of lipid droplets

Lipid droplets (LDs) are crucial organelles for energy storage and lipid homeostasis. Autophagy of LDs is an important pathway for their catabolism, but the molecular mechanisms mediating LD degradation by selective autophagy (lipophagy) are unknown. Here we identify spartin as a receptor localizing...

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Detalles Bibliográficos
Autores principales: Chung, Jeeyun, Park, Joongkyu, Lai, Zon Weng, Lambert, Talley J., Richards, Ruth C., Zhang, Jiuchun, Walther, Tobias C., Farese, Robert V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415183/
https://www.ncbi.nlm.nih.gov/pubmed/37443287
http://dx.doi.org/10.1038/s41556-023-01178-w