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The Troyer syndrome protein spartin mediates selective autophagy of lipid droplets
Lipid droplets (LDs) are crucial organelles for energy storage and lipid homeostasis. Autophagy of LDs is an important pathway for their catabolism, but the molecular mechanisms mediating LD degradation by selective autophagy (lipophagy) are unknown. Here we identify spartin as a receptor localizing...
Autores principales: | Chung, Jeeyun, Park, Joongkyu, Lai, Zon Weng, Lambert, Talley J., Richards, Ruth C., Zhang, Jiuchun, Walther, Tobias C., Farese, Robert V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415183/ https://www.ncbi.nlm.nih.gov/pubmed/37443287 http://dx.doi.org/10.1038/s41556-023-01178-w |
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