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Chitinase-3-like 1 regulates T(H)2 cells, T(FH) cells and IgE responses to helminth infection

INTRODUCTION: Data from patient cohorts and mouse models of atopic dermatitis, food allergy and asthma strongly support a role for chitinase-3-like-1 protein (CHI3L1) in allergic disease. METHODS: To address whether Chi3l1 also contributes to T(H)2 responses following nematode infection, we infected...

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Detalles Bibliográficos
Autores principales: Curtiss, Miranda L., Rosenberg, Alexander F., Scharer, Christopher D., Mousseau, Betty, Benavides, Natalia A. Ballesteros, Bradley, John E., León, Beatriz, Steele, Chad, Randall, Troy D., Lund, Frances E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415220/
https://www.ncbi.nlm.nih.gov/pubmed/37575256
http://dx.doi.org/10.3389/fimmu.2023.1158493