High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase

Actinobacteria possess unique ways to regulate the oxoglutarate metabolic node. Contrary to most organisms in which three enzymes compose the 2-oxoglutarate dehydrogenase complex (ODH), actinobacteria rely on a two-in-one protein (OdhA) in which both the oxidative decarboxylation and succinyl transf...

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Detalles Bibliográficos
Autores principales: Yang, Lu, Wagner, Tristan, Mechaly, Ariel, Boyko, Alexandra, Bruch, Eduardo M., Megrian, Daniela, Gubellini, Francesca, Alzari, Pedro M., Bellinzoni, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415282/
https://www.ncbi.nlm.nih.gov/pubmed/37563123
http://dx.doi.org/10.1038/s41467-023-40253-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415282/
https://www.ncbi.nlm.nih.gov/pubmed/37563123
http://dx.doi.org/10.1038/s41467-023-40253-6

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