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Fine-grained cell-type specific association studies with human bulk brain data using a large single-nucleus RNA sequencing based reference panel

Brain disorders are leading causes of disability worldwide. Gene expression studies provide promising opportunities to better understand their etiology but it is critical that expression is studied on a cell-type level. Cell-type specific association studies can be performed with bulk expression dat...

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Detalles Bibliográficos
Autores principales: van den Oord, Edwin J. C. G., Aberg, Karolina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415334/
https://www.ncbi.nlm.nih.gov/pubmed/37563216
http://dx.doi.org/10.1038/s41598-023-39864-2