HIV-1-induced nuclear invaginations mediated by VAP-A, ORP3, and Rab7 complex explain infection of activated T cells

The mechanism of human immunodeficiency virus 1 (HIV-1) nuclear entry, required for productive infection, is not fully understood. Here, we report that in HeLa cells and activated CD4(+) T cells infected with HIV-1 pseudotyped with VSV-G and native Env protein, respectively, Rab7(+) late endosomes c...

Descripción completa

Detalles Bibliográficos
Autores principales: Santos, Mark F., Rappa, Germana, Karbanová, Jana, Diana, Patrizia, Cirrincione, Girolamo, Carbone, Daniela, Manna, David, Aalam, Feryal, Wang, David, Vanier, Cheryl, Corbeil, Denis, Lorico, Aurelio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415338/
https://www.ncbi.nlm.nih.gov/pubmed/37563144
http://dx.doi.org/10.1038/s41467-023-40227-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415338/
https://www.ncbi.nlm.nih.gov/pubmed/37563144
http://dx.doi.org/10.1038/s41467-023-40227-8

Ejemplares similares