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HIV-1-induced nuclear invaginations mediated by VAP-A, ORP3, and Rab7 complex explain infection of activated T cells
The mechanism of human immunodeficiency virus 1 (HIV-1) nuclear entry, required for productive infection, is not fully understood. Here, we report that in HeLa cells and activated CD4(+) T cells infected with HIV-1 pseudotyped with VSV-G and native Env protein, respectively, Rab7(+) late endosomes c...
Autores principales: | Santos, Mark F., Rappa, Germana, Karbanová, Jana, Diana, Patrizia, Cirrincione, Girolamo, Carbone, Daniela, Manna, David, Aalam, Feryal, Wang, David, Vanier, Cheryl, Corbeil, Denis, Lorico, Aurelio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415338/ https://www.ncbi.nlm.nih.gov/pubmed/37563144 http://dx.doi.org/10.1038/s41467-023-40227-8 |
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