The Effect of Simvastatin on the Dynamics of NF-κB-Regulated Neurodegenerative and Neuroprotective Processes in the Acute Phase of Ischemic Stroke

Statins are lipid-lowering drugs that act by inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase, a rate-limiting enzyme in cholesterol biosynthesis. Animal studies have shown neuroprotective effects of statins in cerebral stroke. However, the underlying mechanisms are not fully understood. T...

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Detalles Bibliográficos
Autores principales: Lietzau, Grazyna, Sienkiewicz, Waldemar, Karwacki, Zbigniew, Dziewiątkowski, Jerzy, Kaleczyc, Jerzy, Kowiański, Przemysław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415422/
https://www.ncbi.nlm.nih.gov/pubmed/37204689
http://dx.doi.org/10.1007/s12035-023-03371-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415422/
https://www.ncbi.nlm.nih.gov/pubmed/37204689
http://dx.doi.org/10.1007/s12035-023-03371-2

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