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Identifying Novel Drug Targets for Epilepsy Through a Brain Transcriptome-Wide Association Study and Protein-Wide Association Study with Chemical-Gene-Interaction Analysis

Epilepsy is a severe neurological condition affecting 50–65 million individuals worldwide that can lead to brain damage. Nevertheless, the etiology of epilepsy remains poorly understood. Meta-analyses of genome-wide association studies involving 15,212 epilepsy cases and 29,677 controls of the ILAE...

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Detalles Bibliográficos
Autores principales: Lu, Mengnan, Feng, Ruoyang, Zhang, Chenglin, Xiao, Yanfeng, Yin, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415436/
https://www.ncbi.nlm.nih.gov/pubmed/37246165
http://dx.doi.org/10.1007/s12035-023-03382-z