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Complement C3 Enhances LPS-Elicited Neuroinflammation and Neurodegeneration Via the Mac1/NOX2 Pathway

Recent studies showed increased expression of complements in various neurodegenerative diseases, including Alzheimer’s and Parkinson’s diseases. However, the mechanism regulating the expression of complements and their roles in the pathogenesis of neurodegeneration are unclear. We hypothesized that...

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Detalles Bibliográficos
Autores principales: Zhou, Ran, Chen, Shih-Heng, Zhao, Zhan, Tu, Dezhen, Song, Sheng, Wang, Yubao, Wang, Qingshan, Feng, Jing, Hong, Jau-Shyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415527/
https://www.ncbi.nlm.nih.gov/pubmed/37268807
http://dx.doi.org/10.1007/s12035-023-03393-w