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A novel LncRNA SPIRE1/miR-181a-5p/PRLR axis in mandibular bone marrow–derived mesenchymal stem cells regulates the Th17/Treg immune balance through the JAK/STAT3 pathway in periodontitis

Periodontitis is a microbial-related chronic inflammatory disease associated with imbalanced differentiation of Th17 cells and Treg cells. Bone marrow-derived mesenchymal stem cells (BM-MSCs) possess wide immunoregulatory properties. Long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) contribute to...

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Detalles Bibliográficos
Autores principales: Shao, Bingyi, Zhou, Duo, Wang, Jie, Yang, Deqin, Gao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415575/
https://www.ncbi.nlm.nih.gov/pubmed/37490712
http://dx.doi.org/10.18632/aging.204895