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Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span

The decrease in the podocyte’s lifespan and health-span that typify healthy kidney aging cause a decrease in their normal structure, physiology and function. The ability to halt and even reverse these changes becomes clinically relevant when disease is superimposed on an aged kidney. RNA-sequencing...

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Detalles Bibliográficos
Autores principales: Kaverina, Natalya, Schweickart, R. Allen, Chan, Gek Cher, Maggiore, Joseph C., Eng, Diana G., Zeng, Yuting, McKinzie, Sierra R., Perry, Hannah S., Ali, Adilijiang, O’Connor, Christopher, Pereira, Beatriz Maria Veloso, Theberge, Ashleigh B., Vaughan, Joshua C., Loretz, Carol J., Chang, Anthony, Hukriede, Neil A., Bitzer, Markus, Pippin, Jeffrey W., Wessely, Oliver, Shankland, Stuart J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415579/
https://www.ncbi.nlm.nih.gov/pubmed/37487005
http://dx.doi.org/10.18632/aging.204897