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Parenchymal border macrophages regulate tau pathology and tau-mediated neurodegeneration

Parenchymal border macrophages (PBMs) reside close to the central nervous system parenchyma and regulate CSF flow dynamics. We recently demonstrated that PBMs provide a clearance pathway for amyloid-β peptide, which accumulates in the brain in Alzheimer’s disease (AD). Given the emerging role for PB...

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Detalles Bibliográficos
Autores principales: Drieu, Antoine, Du, Siling, Kipnis, Michal, Bosch, Megan E, Herz, Jasmin, Lee, Choonghee, Jiang, Hong, Manis, Melissa, Ulrich, Jason D, Kipnis, Jonathan, Holtzman, David M, Gratuze, Maud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415611/
https://www.ncbi.nlm.nih.gov/pubmed/37562846
http://dx.doi.org/10.26508/lsa.202302087