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Sustained notch signaling inhibition with a gamma-secretase inhibitor prevents traumatic heterotopic ossification

BACKGROUND: Traumatic heterotopic ossification (THO) is a devastating sequela following traumatic injuries and orthopedic surgeries. To date, the exact molecular mechanism of THO formation is still unclear, which hinders the development of effective treatments. The process of THO formation is believ...

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Detalles Bibliográficos
Autores principales: Wang, Zheng, Yi, Xinzeyu, Jian, Chao, Qi, Baiwen, Liu, Qiaoyun, Li, Zonghuan, Yu, Aixi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415638/
https://www.ncbi.nlm.nih.gov/pubmed/37575153
http://dx.doi.org/10.1016/j.jot.2023.06.004