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Sustained notch signaling inhibition with a gamma-secretase inhibitor prevents traumatic heterotopic ossification
BACKGROUND: Traumatic heterotopic ossification (THO) is a devastating sequela following traumatic injuries and orthopedic surgeries. To date, the exact molecular mechanism of THO formation is still unclear, which hinders the development of effective treatments. The process of THO formation is believ...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Chinese Speaking Orthopaedic Society
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415638/ https://www.ncbi.nlm.nih.gov/pubmed/37575153 http://dx.doi.org/10.1016/j.jot.2023.06.004 |