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5-HT(1A) and 5-HT(2B) receptor interaction and co-clustering regulate serotonergic neuron excitability

Many psychiatric diseases have been associated with serotonin (5-HT) neuron dysfunction. The firing of 5-HT neurons is known to be under 5-HT(1A) receptor-mediated autoinhibition, but functional consequences of coexpressed receptors are unknown. Using co-immunoprecipitation, BRET, confocal, and supe...

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Detalles Bibliográficos
Autores principales: Benhadda, Amina, Delhaye, Célia, Moutkine, Imane, Marques, Xavier, Russeau, Marion, Le Magueresse, Corentin, Roumier, Anne, Lévi, Sabine, Maroteaux, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415917/
https://www.ncbi.nlm.nih.gov/pubmed/37575185
http://dx.doi.org/10.1016/j.isci.2023.107401