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Homo-oxidized HSPB1 protects H9c2 cells against oxidative stress via activation of KEAP1/NRF2 signaling pathway

Several heat shock proteins are implicated in the endogenous cardioprotective mechanisms, but little is known about the role of heat shock protein beta-1 (HSPB1). This study aims to investigate the oxidation state and role of HSPB1 in cardiomyocytes undergoing oxidative stress and underlying mechani...

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Detalles Bibliográficos
Autores principales: Wang, Nian, Liu, Xiehong, Liu, Ke, Wang, Kangkai, Zhang, Huali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415933/
https://www.ncbi.nlm.nih.gov/pubmed/37575200
http://dx.doi.org/10.1016/j.isci.2023.107443