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Respiratory complex I in mitochondrial membrane catalyzes oversized ubiquinones

NADH-ubiquinone (UQ) oxidoreductase (complex I) couples electron transfer from NADH to UQ with proton translocation in its membrane part. The UQ reduction step is key to triggering proton translocation. Structural studies have identified a long, narrow, tunnel-like cavity within complex I, through w...

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Detalles Bibliográficos
Autores principales: Ikunishi, Ryo, Otani, Ryohei, Masuya, Takahiro, Shinzawa-Itoh, Kyoko, Shiba, Tomoo, Murai, Masatoshi, Miyoshi, Hideto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416054/
https://www.ncbi.nlm.nih.gov/pubmed/37394006
http://dx.doi.org/10.1016/j.jbc.2023.105001