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Myo1d promotes alpha-synuclein transfer from brain microvascular endothelial cells to pericytes through tunneling nanotubes

α-Synuclein preformed fibrils (α-syn PFF) in the blood can cross the blood–brain barrier and invade the central nervous system. Our previous study proved that α-syn PFF can be taken up by brain microvascular endothelial cells (BMVECs). Here, we found that α-syn PFF spread from BMVECs to pericytes wi...

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Detalles Bibliográficos
Autores principales: Duan, Qingrui, Zhang, Qingxi, Nie, Kun, Huang, Rui, Yang, Jianhua, He, Peikun, Tie, Zihui, Huang, Haifeng, Ma, Guixian, Zhang, Yuhu, Gao, Yuyuan, Wang, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416064/
https://www.ncbi.nlm.nih.gov/pubmed/37575183
http://dx.doi.org/10.1016/j.isci.2023.107458