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Myo1d promotes alpha-synuclein transfer from brain microvascular endothelial cells to pericytes through tunneling nanotubes
α-Synuclein preformed fibrils (α-syn PFF) in the blood can cross the blood–brain barrier and invade the central nervous system. Our previous study proved that α-syn PFF can be taken up by brain microvascular endothelial cells (BMVECs). Here, we found that α-syn PFF spread from BMVECs to pericytes wi...
Autores principales: | Duan, Qingrui, Zhang, Qingxi, Nie, Kun, Huang, Rui, Yang, Jianhua, He, Peikun, Tie, Zihui, Huang, Haifeng, Ma, Guixian, Zhang, Yuhu, Gao, Yuyuan, Wang, Lijuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416064/ https://www.ncbi.nlm.nih.gov/pubmed/37575183 http://dx.doi.org/10.1016/j.isci.2023.107458 |
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