Heme binding to the SARS-CoV-2 spike glycoprotein

The target for humoral immunity, SARS-CoV-2 spike glycoprotein, has become the focus of vaccine research and development. Previous work demonstrated that the N-terminal domain (NTD) of SARS-CoV-2 spike binds biliverdin—a product of heme catabolism—causing a strong allosteric effect on the activity o...

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Detalles Bibliográficos
Autores principales: Freeman, Samuel L., Oliveira, A. Sofia F., Gallio, Andrea E., Rosa, Annachiara, Simitakou, Maria K., Arthur, Christopher J., Mulholland, Adrian J., Cherepanov, Peter, Raven, Emma L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416065/
https://www.ncbi.nlm.nih.gov/pubmed/37414149
http://dx.doi.org/10.1016/j.jbc.2023.105014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416065/
https://www.ncbi.nlm.nih.gov/pubmed/37414149
http://dx.doi.org/10.1016/j.jbc.2023.105014

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