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Influence of EGF and pro-NGF on EGFR/SORTILIN interaction and clinical impact in head and neck squamous cell carcinoma

Head and Neck Squamous Cell Carcinoma (HNSCC) remains a cancer with a poor prognosis, with a 5-year survival rate of less than 50%. Although epidermal growth factor receptor (EGFR) is almost always overexpressed, targeted anti-EGFR therapies have modest efficacy and are mainly used in palliative car...

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Detalles Bibliográficos
Autores principales: Morisse, Martin, Bourhis, Thomas, Lévêque, Romain, Guilbert, Mathieu, Cicero, Julien, Palma, Martine, Chevalier, Dominique, le Bourhis, Xuefen, Toillon, Robert-Alain, Mouawad, Francois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416107/
https://www.ncbi.nlm.nih.gov/pubmed/37576898
http://dx.doi.org/10.3389/fonc.2023.661775