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Chimeric d/l-DNA Probes of Base Excision Repair Enable Real-Time Monitoring of Thymine DNA Glycosylase Activity in Live Cells

[Image: see text] The base excision repair (BER) pathway is a frontline defender of genomic integrity and plays a central role in epigenetic regulation through its involvement in the erasure of 5-methylcytosine. This biological and clinical significance has led to a demand for analytical methods cap...

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Detalles Bibliográficos
Autores principales: Zhong, Wenrui, Sczepanski, Jonathan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416308/
https://www.ncbi.nlm.nih.gov/pubmed/37493592
http://dx.doi.org/10.1021/jacs.3c03010