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The effects of esketamine and treatment expectation in acute major depressive disorder (Expect): study protocol for a pharmacological fMRI study using a balanced placebo design

BACKGROUND: Major depressive disorder (MDD) is a highly prevalent (8–15%), severely disabling disorder and is associated with enormous socioeconomic impact. Antidepressant medication for the treatment of MDD has proven effective in RCTs; however, placebo response is also substantial. Given the poten...

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Detalles Bibliográficos
Autores principales: Falkenberg, Irina, Bitsch, Florian, Liu, Wei, Matsingos, Alexandros, Noor, Laila, Vogelbacher, Christoph, Yildiz, Cüneyt, Kircher, Tilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416369/
https://www.ncbi.nlm.nih.gov/pubmed/37568215
http://dx.doi.org/10.1186/s13063-023-07556-x