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Diminished activation of excitatory neurons in the prelimbic cortex leads to impaired working memory capacity in mice

BACKGROUND: Working memory capacity impairment is an early sign of Alzheimer's disease, but the underlying mechanisms remain unclear. Clarifying how working memory capacity is affected will help us better understand the pathological mechanism of Alzheimer's disease. We used the olfactory w...

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Detalles Bibliográficos
Autores principales: Jiang, Li-Xin, Huang, Geng-Di, Tian, Yong-Lu, Cong, Ri-Xu, Meng, Xue, Wang, Hua-Li, Zhang, Chen, Yu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416384/
https://www.ncbi.nlm.nih.gov/pubmed/37568146
http://dx.doi.org/10.1186/s12915-023-01674-3