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A mannitol-modified emodin nano-drug restores the intestinal barrier function and alleviates inflammation in a mouse model of DSS-induced ulcerative colitis

BACKGROUND: Ulcerative colitis (UC) is an inflammatory disease of the colon that is characterized by mucosal ulcers. Given its increasing prevalence worldwide, it is imperative to develop safe and effective drugs for treating UC. Emodin, a natural anthraquinone derivative present in various medicina...

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Detalles Bibliográficos
Autores principales: Xu, Yin-Yue, Zhu, Min, Wu, Jiang, Luo, Long-Biao, Dong, Si-jing, Zhang, Meng-Gai, Liu, Xue, Wang, Ke, Luo, Hua, Jing, Wang-Hui, Wang, Lin, Wang, Si-Cen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416390/
https://www.ncbi.nlm.nih.gov/pubmed/37568235
http://dx.doi.org/10.1186/s13020-023-00801-0