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A mannitol-modified emodin nano-drug restores the intestinal barrier function and alleviates inflammation in a mouse model of DSS-induced ulcerative colitis
BACKGROUND: Ulcerative colitis (UC) is an inflammatory disease of the colon that is characterized by mucosal ulcers. Given its increasing prevalence worldwide, it is imperative to develop safe and effective drugs for treating UC. Emodin, a natural anthraquinone derivative present in various medicina...
Autores principales: | Xu, Yin-Yue, Zhu, Min, Wu, Jiang, Luo, Long-Biao, Dong, Si-jing, Zhang, Meng-Gai, Liu, Xue, Wang, Ke, Luo, Hua, Jing, Wang-Hui, Wang, Lin, Wang, Si-Cen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416390/ https://www.ncbi.nlm.nih.gov/pubmed/37568235 http://dx.doi.org/10.1186/s13020-023-00801-0 |
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