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The Hippo signaling pathway contributes to the 2,5-Hexadion-induced apoptosis of ovarian granulosa cells

Although n-hexane can induce ovarian damage by inducing ovarian granulosa cell (GC) apoptosis, the mechanism underlying this induction of apoptosis has not been fully elucidated. In this study, rat ovarian GCs were exposed to different concentrations of 2,5-hexanedione (2,5-HD) (the main metabolite...

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Detalles Bibliográficos
Autores principales: Sun, Yi, Chen, Huiting, Chen, Sichuan, Xu, Xueming, Zhang, Wenchang, Li, Yuchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416496/
https://www.ncbi.nlm.nih.gov/pubmed/37563629
http://dx.doi.org/10.1186/s13048-023-01249-4