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N6-methyladenosine (m6A) methyltransferase WTAP-mediated miR-92b-5p accelerates osteoarthritis progression

The study was design to investigate the functional roles of Wilms tumor 1-associated protein (WTAP), an enzyme catalyzes m6A modification, in the pathogenesis of osteoarthritis (OA) and further elucidate its possible regulatory mechanism. Herein, we discovered that WTAP was outstandingly upregulated...

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Detalles Bibliográficos
Autores principales: Lin, Zhaowei, Jiang, Tao, Zheng, Wei, Zhang, Jiayuan, Li, Anan, Lu, Chao, Liu, Wengang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416510/
https://www.ncbi.nlm.nih.gov/pubmed/37563688
http://dx.doi.org/10.1186/s12964-023-01228-8