Iron-based metal-organic framework co-loaded with buthionine sulfoximine and oxaliplatin for enhanced cancer chemo-ferrotherapy via sustainable glutathione elimination

BACKGROUND: Emerging ferroptosis-driven therapies based on nanotechnology function either by increasing intracellular iron level or suppressing glutathione peroxidase 4 (GPX4) activity. Nevertheless, the therapeutic strategy of simultaneous iron delivery and GPX4 inhibition remains challenging and h...

Descripción completa

Detalles Bibliográficos
Autores principales: Rao, Zhiping, Xia, Yutian, Jia, Qian, Zhu, Yutong, Wang, Lexuan, Liu, Guohuan, Liu, Xuelan, Yang, Peng, Ning, Pengbo, Zhang, Ruili, Zhang, Xianghan, Qiao, Chaoqiang, Wang, Zhongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416514/
https://www.ncbi.nlm.nih.gov/pubmed/37563614
http://dx.doi.org/10.1186/s12951-023-01998-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416514/
https://www.ncbi.nlm.nih.gov/pubmed/37563614
http://dx.doi.org/10.1186/s12951-023-01998-w

Ejemplares similares