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Iron-based metal-organic framework co-loaded with buthionine sulfoximine and oxaliplatin for enhanced cancer chemo-ferrotherapy via sustainable glutathione elimination

BACKGROUND: Emerging ferroptosis-driven therapies based on nanotechnology function either by increasing intracellular iron level or suppressing glutathione peroxidase 4 (GPX4) activity. Nevertheless, the therapeutic strategy of simultaneous iron delivery and GPX4 inhibition remains challenging and h...

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Detalles Bibliográficos
Autores principales:	Rao, Zhiping, Xia, Yutian, Jia, Qian, Zhu, Yutong, Wang, Lexuan, Liu, Guohuan, Liu, Xuelan, Yang, Peng, Ning, Pengbo, Zhang, Ruili, Zhang, Xianghan, Qiao, Chaoqiang, Wang, Zhongliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416514/ https://www.ncbi.nlm.nih.gov/pubmed/37563614 http://dx.doi.org/10.1186/s12951-023-01998-w

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