Combination strategies to overcome drug resistance in FLT(+) acute myeloid leukaemia

BACKGROUND: Acute myeloid leukaemia (AML) remains difficult to treat despite the development of novel formulations and targeted therapies. Activating mutations in the FLT3 gene are common among patients and make the tumour susceptible to FLT3 inhibitors, but resistance to such inhibitors develops qu...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Jingmei, Friedman, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416533/
https://www.ncbi.nlm.nih.gov/pubmed/37568211
http://dx.doi.org/10.1186/s12935-023-03000-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416533/
https://www.ncbi.nlm.nih.gov/pubmed/37568211
http://dx.doi.org/10.1186/s12935-023-03000-x

Ejemplares similares