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Combination strategies to overcome drug resistance in FLT(+) acute myeloid leukaemia
BACKGROUND: Acute myeloid leukaemia (AML) remains difficult to treat despite the development of novel formulations and targeted therapies. Activating mutations in the FLT3 gene are common among patients and make the tumour susceptible to FLT3 inhibitors, but resistance to such inhibitors develops qu...
Autores principales: | Yang, Jingmei, Friedman, Ran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416533/ https://www.ncbi.nlm.nih.gov/pubmed/37568211 http://dx.doi.org/10.1186/s12935-023-03000-x |
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