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TGFβ Inhibitor A83-01 Enhances Murine HSPC Expansion for Gene Therapy
Murine hematopoietic stem and progenitor cells (HSPCs) are commonly used as model systems during gene therapeutic retroviral vector development and preclinical biosafety assessment. Here, we developed cell culture conditions to maintain stemness and prevent differentiation during HSPC culture. We us...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10416825/ https://www.ncbi.nlm.nih.gov/pubmed/37566057 http://dx.doi.org/10.3390/cells12151978 |