Tumor Mutational Burden in Breast Cancer: Current Evidence, Challenges, and Opportunities

SIMPLE SUMMARY: The tumor mutational burden (TMB) can be defined as the number of somatic mutations per megabase of the sequenced genome. It correlates with tumor neoantigen burden, T cell infiltration, and response to immune checkpoint inhibitors in many solid tumor types. In addition, TMB has been...

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Detalles Bibliográficos
Autores principales: Barroso-Sousa, Romualdo, Pacífico, Jana Priscila, Sammons, Sarah, Tolaney, Sara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417019/
https://www.ncbi.nlm.nih.gov/pubmed/37568813
http://dx.doi.org/10.3390/cancers15153997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417019/
https://www.ncbi.nlm.nih.gov/pubmed/37568813
http://dx.doi.org/10.3390/cancers15153997

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