Intraocular Adeno-Associated Virus-Mediated Transgene Endothelin-1 Delivery to the Rat Eye Induces Functional Changes Indicative of Retinal Ischemia—A Potential Chronic Glaucoma Model

Endothelin-1 (ET-1) overactivity has been implicated as a factor contributing to glaucomatous neuropathy, and it has been utilized in animal models of retinal ischemia. The functional effects of long-term ET-1 exposure and possible compensatory mechanisms have, however, not been investigated. This w...

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Detalles Bibliográficos
Autores principales: Nordahl, Karin M. L., Fedulov, Vadim, Holm, Anja, Haanes, Kristian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417058/
https://www.ncbi.nlm.nih.gov/pubmed/37566067
http://dx.doi.org/10.3390/cells12151987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417058/
https://www.ncbi.nlm.nih.gov/pubmed/37566067
http://dx.doi.org/10.3390/cells12151987

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