Cargando…

Intraocular Adeno-Associated Virus-Mediated Transgene Endothelin-1 Delivery to the Rat Eye Induces Functional Changes Indicative of Retinal Ischemia—A Potential Chronic Glaucoma Model

Endothelin-1 (ET-1) overactivity has been implicated as a factor contributing to glaucomatous neuropathy, and it has been utilized in animal models of retinal ischemia. The functional effects of long-term ET-1 exposure and possible compensatory mechanisms have, however, not been investigated. This w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nordahl, Karin M. L., Fedulov, Vadim, Holm, Anja, Haanes, Kristian A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417058/ https://www.ncbi.nlm.nih.gov/pubmed/37566067 http://dx.doi.org/10.3390/cells12151987

Ejemplares similares

Enhanced Endothelin-1 Mediated Vasoconstriction of the Ophthalmic Artery May Exacerbate Retinal Damage after Transient Global Cerebral Ischemia in Rat
por: Blixt, Frank W., et al.
Publicado: (2016)

Intraocular Foreign Body Causing Retinal and Choroidal Ischemia
por: Kim, Jae Gon, et al.
Publicado: (2020)

Endothelin B Receptors Contribute to Retinal Ganglion Cell Loss in a Rat Model of Glaucoma
por: Minton, Alena Z., et al.
Publicado: (2012)

Glaucoma severity and intraocular pressure reduction after cataract surgery in eyes with medically controlled glaucoma
por: Yoo, Chungkwon, et al.
Publicado: (2018)

Retinal venous pressure: the role of endothelin
por: Flammer, Josef, et al.
Publicado: (2015)

Glaucoma and intraocular pressure in EPIC-Norfolk Eye Study: cross sectional study
por: Chan, Michelle P Y, et al.
Publicado: (2017)

EyeCee One preloaded intraocular lens: are patients with glaucoma more at risk?
por: Jones, Ruth K, et al.
Publicado: (2023)

Endothelin Receptors, Mitochondria and Neurogenesis in Cerebral Ischemia
por: Gulati, Anil
Publicado: (2016)

Endothelin System and Ischemia-Induced Ventricular Tachyarrhythmias
por: Mouchtouri, Eleni-Taxiarchia, et al.
Publicado: (2022)

Plasma endothelin-1 and single nucleotide polymorphisms of endothelin-1 and endothelin type A receptor genes as risk factors for normal tension glaucoma
por: Kosior-Jarecka, Ewa, et al.
Publicado: (2016)

Improving adeno-associated viral (AAV) vector-mediated transgene expression in retinal ganglion cells: comparison of five promoters
por: Nieuwenhuis, Bart, et al.
Publicado: (2023)

Risk Factors in Normal-Tension Glaucoma and High-Tension Glaucoma in relation to Polymorphisms of Endothelin-1 Gene and Endothelin-1 Receptor Type A Gene
por: Wróbel-Dudzińska, Dominika, et al.
Publicado: (2015)

Glaucoma through Animal’s Eyes: Insights from the Evolution of Intraocular Pressure in Mammals and Birds
por: Hongjamrassilp, Watcharapong, et al.
Publicado: (2022)

Bionic eye system mimicking microfluidic structure and intraocular pressure for glaucoma surgery training
por: Yamanaka, Toshiro, et al.
Publicado: (2022)

Outcomes of lensectomy with glued intraocular lens and factors associated with failure in eyes with spherophakia and glaucoma
por: Burugupally, Keerthi, et al.
Publicado: (2023)

Vascular derived endothelin receptor A controls endothelin-induced retinal ganglion cell death
por: Marola, Olivia J., et al.
Publicado: (2022)

Inter-eye comparison of retinal oximetry and vessel caliber between eyes with asymmetrical glaucoma severity in different glaucoma subtypes
por: Cheng, Clarissa Shu Ming, et al.
Publicado: (2016)

Adeno-associated Virus-mediated, Mifepristone-regulated Transgene Expression in the Brain
por: Maddalena, Andrea, et al.
Publicado: (2013)

Comparison of changes in retinal nerve fiber layer thickness and intraocular pressure between glaucoma and non-glaucoma patients after phacoemulsification
por: Shahid, Maryam, et al.
Publicado: (2023)

Disruption of 24-Hour Rhythm in Intraocular Pressure Correlates with Retinal Ganglion Cell Loss in Glaucoma
por: Neroev, Vladimir, et al.
Publicado: (2020)

A narrative review on the association of high intraocular pressure and glaucoma in patients with retinal vein occlusion
por: Jabbehdari, Sayena, et al.
Publicado: (2022)

Diurnal variation in central corneal thickness and intraocular pressure in eyes with pseudoexfoliation syndrome without glaucoma
por: Keel, Stuart, et al.
Publicado: (2014)

Intraocular Pressure Control after Implantation of an Ahmed Glaucoma Valve in Eyes with a Failed Trabeculectomy
por: Schimiti, Rui B, et al.
Publicado: (2016)

Comparison of the Visual Outcomes of Enhanced and Standard Monofocal Intraocular Lens Implantations in Eyes with Early Glaucoma
por: Nam, Jeoung Woo, et al.
Publicado: (2023)

Retinal and Corneal Toxicity and Pharmacokinetic Analysis of Intraocular Injection of Ganciclovir in Rabbit Eyes
por: Sun, Bin-jia, et al.
Publicado: (2019)

Response of the Trilaminar Retinal Vessel Network to Intraocular Pressure Elevation in Rat Eyes
por: Zhao, Da, et al.
Publicado: (2020)

Activation of Autophagy in a Rat Model of Retinal Ischemia following High Intraocular Pressure
por: Piras, Antonio, et al.
Publicado: (2011)

Mitochondrial Dysfunction in a High Intraocular Pressure-Induced Retinal Ischemia Minipig Model
por: Pasák, Michael, et al.
Publicado: (2022)

Endothelin-1 Role in Human Eye: A Review
por: Salvatore, Serena, et al.
Publicado: (2010)

Riboswitches for Controlled Expression of Therapeutic Transgenes Delivered by Adeno-Associated Viral Vectors
por: Tickner, Zachary J., et al.
Publicado: (2021)

Muscle regeneration affects Adeno Associated Virus 1 mediated transgene transcription
por: Mollard, Amédée, et al.
Publicado: (2022)

The Intraocular Serous Membrane and the Nature of Glaucoma
por: Sichel, A.
Publicado: (1871)

Retinal Thickness and the Structure/Function Relationship in the Eyes of Older Adults with Glaucoma
por: Honjo, Megumi, et al.
Publicado: (2015)

Retinal arterial pulsation as an indicator of raised intraocular pressure
por: Berrett, George Benjamin, et al.
Publicado: (2021)

Alterations of the synapse of the inner retinal layers after chronic intraocular pressure elevation in glaucoma animal model
por: Park, Hae-Young Lopilly, et al.
Publicado: (2014)

Intraocular cytokine profile and autoimmune reactions in retinitis pigmentosa, age‐related macular degeneration, glaucoma and cataract
por: ten Berge, Josianne C., et al.
Publicado: (2018)

Effects of oral Mirtogenol on retinal ganglion cell apoptosis index and intraocular pressure in the Wistar glaucoma model
por: Andika, Yustiadenta Widya, et al.
Publicado: (2023)

Analysis of Korean Retinal Specialists’ Opinions on Implanting Diffractive Multifocal Intraocular Lenses in Eyes with Underlying Retinal Diseases
por: Lee, Jung-Hwa, et al.
Publicado: (2022)

Intraocular pressure 1 year after vitrectomy in eyes without a history of glaucoma or ocular hypertension
por: Fang, Yuan, et al.
Publicado: (2017)

Siderotic glaucoma without detectable intraocular foreign body in a pseudophakic eye: a case report
por: Huang, Yang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_88bqr30qemouthi9t4j30thtca