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Inhibition of FGFR3 upregulates MHC‐I and PD‐L1 via TLR3/NF‐kB pathway in muscle‐invasive bladder cancer

BACKGROUND: Improving the potency of immune response is paramount among issues concerning immunotherapy of muscle‐invasive bladder cancer (MIBC). METHODS: On the basis of immune subtypes, we investigated possible molecular mechanisms involved in tumor immune escape in MIBC. According to the 312 immu...

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Detalles Bibliográficos
Autores principales: Wu, WenBo, Chen, Lei, Jia, GaoZhen, Tang, QiLin, Han, BangMin, Xia, ShuJie, Jiang, Qi, Liu, HaiTao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417096/
https://www.ncbi.nlm.nih.gov/pubmed/37283287
http://dx.doi.org/10.1002/cam4.6172