Antibody–Drug Conjugates: A Review of Approved Drugs and Their Clinical Level of Evidence

SIMPLE SUMMARY: Antibody–drug conjugates (ADC) have shown remarkable therapeutic activity in a wide range of hematologic and solid tumors. Herein, we discuss the mechanisms of action of ADCs, the desirable “bystander killing”, and the limitations associated with the design of each drug. We will also...

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Detalles Bibliográficos
Autores principales: Gogia, Pooja, Ashraf, Hamza, Bhasin, Sidharth, Xu, Yiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417123/
https://www.ncbi.nlm.nih.gov/pubmed/37568702
http://dx.doi.org/10.3390/cancers15153886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417123/
https://www.ncbi.nlm.nih.gov/pubmed/37568702
http://dx.doi.org/10.3390/cancers15153886

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