Unveiling the Role of Cholesterol in Subnanomolar Ouabain Rescue of Cortical Neurons from Calcium Overload Caused by Excitotoxic Insults

Na/K-ATPase maintains transmembrane ionic gradients and acts as a signal transducer when bound to endogenous cardiotonic steroids. At subnanomolar concentrations, ouabain induces neuroprotection against calcium overload and apoptosis of neurons during excitotoxic stress. Here, the role of lipid raft...

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Detalles Bibliográficos
Autores principales: Sibarov, Dmitry A., Zhuravleva, Zoia D., Ilina, Margarita A., Boikov, Sergei I., Stepanenko, Yulia D., Karelina, Tatiana V., Antonov, Sergei M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417153/
https://www.ncbi.nlm.nih.gov/pubmed/37566090
http://dx.doi.org/10.3390/cells12152011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417153/
https://www.ncbi.nlm.nih.gov/pubmed/37566090
http://dx.doi.org/10.3390/cells12152011

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