Genomic landscape of locally advanced rectal adenocarcinoma: Comparison between before and after neoadjuvant chemoradiation and effects of genetic biomarkers on clinical outcomes and tumor response

PURPOSE: To explore genomic biomarkers in rectal cancer by performing whole‐exome sequencing. MATERIALS AND METHODS: Pre‐chemoradiation (CRT) biopsy and post‐CRT surgical specimens were obtained from 27 patients undergoing neoadjuvant CRT followed by definitive resection. Exomes were sequenced to a...

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Detalles Bibliográficos
Autores principales: Lee, Tae Hoon, Jang, Bum‐Sup, Chang, Ji Hyun, Kim, Eunji, Park, Jeong Hwan, Chie, Eui Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417181/
https://www.ncbi.nlm.nih.gov/pubmed/37260182
http://dx.doi.org/10.1002/cam4.6169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417181/
https://www.ncbi.nlm.nih.gov/pubmed/37260182
http://dx.doi.org/10.1002/cam4.6169

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