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ATAXIA TELANGIECTASIA MUTATED PROTECTS AGAINST LIPOPOLYSACCARIDE-INDUCED BLOOD-BRAIN BARRIER DISRUPTION BY REGULATING ATK/DRP1-MEDIATED MITOCHONDRIAL HOMEOSTASIS

Background: Protein kinase ataxia telangiectasia mutated (ATM) regulates the function of endothelial cells and responds quickly to endotoxin. However, the function of ATM in lipopolysaccharide (LPS)-induced blood-brain barrier (BBB) disruption remains unknown. This study aimed to investigate the rol...

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Detalles Bibliográficos
Autores principales: Luo, Shiyuan, Lyu, Zhuochen, Ge, Lingling, Li, Yinjiao, Liu, Yuqi, Yuan, Yuan, Zhao, Rui, Huang, Lei, Zhao, Jianyuan, Huang, Hongjun, Luo, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417231/
https://www.ncbi.nlm.nih.gov/pubmed/37141173
http://dx.doi.org/10.1097/SHK.0000000000002139