HCS-Splice: A High-Content Screening Method to Advance the Discovery of RNA Splicing-Modulating Therapeutics

Nucleic acid therapeutics have demonstrated an impressive acceleration in recent years. They work through multiple mechanisms of action, including the downregulation of gene expression and the modulation of RNA splicing. While several drugs based on the former mechanism have been approved, few targe...

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Detalles Bibliográficos
Autores principales: Covello, Giuseppina, Siva, Kavitha, Adami, Valentina, Denti, Michela Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417277/
https://www.ncbi.nlm.nih.gov/pubmed/37566038
http://dx.doi.org/10.3390/cells12151959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417277/
https://www.ncbi.nlm.nih.gov/pubmed/37566038
http://dx.doi.org/10.3390/cells12151959

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