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HCS-Splice: A High-Content Screening Method to Advance the Discovery of RNA Splicing-Modulating Therapeutics
Nucleic acid therapeutics have demonstrated an impressive acceleration in recent years. They work through multiple mechanisms of action, including the downregulation of gene expression and the modulation of RNA splicing. While several drugs based on the former mechanism have been approved, few targe...
Autores principales: | Covello, Giuseppina, Siva, Kavitha, Adami, Valentina, Denti, Michela Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417277/ https://www.ncbi.nlm.nih.gov/pubmed/37566038 http://dx.doi.org/10.3390/cells12151959 |
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