PP2A-Mediated GSK3β Dephosphorylation Is Required for Protocadherin-7-Dependent Regulation of Small GTPase RhoA in Osteoclasts

Protocadherin-7 (Pcdh7) is a member of the non-clustered protocadherin δ1 subgroup of the cadherin superfamily. Pcdh7 has been revealed to control osteoclast differentiation by regulating Rho-family small GTPases, RhoA and Rac1, through its intracellular SET binding domain. However, the mechanisms b...

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Detalles Bibliográficos
Autores principales: Kim, Hyunsoo, Takegahara, Noriko, Choi, Yongwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417323/
https://www.ncbi.nlm.nih.gov/pubmed/37566044
http://dx.doi.org/10.3390/cells12151967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417323/
https://www.ncbi.nlm.nih.gov/pubmed/37566044
http://dx.doi.org/10.3390/cells12151967

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