Α Humanized RANKL Transgenic Mouse Model of Progestin-Induced Mammary Carcinogenesis for Evaluation of Novel Therapeutics

SIMPLE SUMMARY: Targeting receptor activator of nuclear factor-κB ligand (RANKL) with the monoclonal antibody Denosumab decreases osteoclast-mediated bone resorption and is approved for the treatment of postmenopausal osteoporosis. Since RANKL is also implicated in mammary gland homeostasis and brea...

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Detalles Bibliográficos
Autores principales: Kolokotroni, Anthi, Gkikopoulou, Evi, Rinotas, Vagelis, Ntari, Lydia, Zareifi, Danae, Rouchota, Maritina, Sarpaki, Sophia, Lymperopoulos, Ilias, Alexopoulos, Leonidas G., Loudos, George, Denis, Maria C., Karagianni, Niki, Douni, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417415/
https://www.ncbi.nlm.nih.gov/pubmed/37568820
http://dx.doi.org/10.3390/cancers15154006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417415/
https://www.ncbi.nlm.nih.gov/pubmed/37568820
http://dx.doi.org/10.3390/cancers15154006

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