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PAI-1 Regulation of p53 Expression and Senescence in Type II Alveolar Epithelial Cells

Cellular senescence contributes importantly to aging and aging-related diseases, including idiopathic pulmonary fibrosis (IPF). Alveolar epithelial type II (ATII) cells are progenitors of alveolar epithelium, and ATII cell senescence is evident in IPF. Previous studies from this lab have shown that...

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Detalles Bibliográficos
Autores principales: Rana, Tapasi, Jiang, Chunsun, Banerjee, Sami, Yi, Nengjun, Zmijewski, Jaroslaw W., Liu, Gang, Liu, Rui-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417428/
https://www.ncbi.nlm.nih.gov/pubmed/37566086
http://dx.doi.org/10.3390/cells12152008