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StemRegenin-1 Attenuates Endothelial Progenitor Cell Senescence by Regulating the AhR Pathway-Mediated CYP1A1 and ROS Generation

Endothelial progenitor cell (EPC)-based stem cell therapy is a promising therapeutic strategy for vascular diseases. However, continuous in vitro expansion for clinical studies induces the loss of EPC functionality due to aging. In this study, we investigated the effects of StemRegenin-1 (SR-1), an...

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Detalles Bibliográficos
Autores principales: Lim, Hye Ji, Jang, Woong Bi, Rethineswaran, Vinoth Kumar, Choi, Jaewoo, Lee, Eun Ji, Park, Sangmi, Jeong, Yeoreum, Ha, Jong Seong, Yun, Jisoo, Choi, Young Jin, Hong, Young Joon, Kwon, Sang-Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417434/
https://www.ncbi.nlm.nih.gov/pubmed/37566085
http://dx.doi.org/10.3390/cells12152005