MAGI1 Prevents Senescence and Promotes the DNA Damage Response in ER(+) Breast Cancer

MAGI1 acts as a tumor suppressor in estrogen receptor-positive (ER(+)) breast cancer (BC), and its loss correlates with a more aggressive phenotype. To identify the pathways and events affected by MAGI1 loss, we deleted the MAGI1 gene in the ER(+) MCF7 BC cell line and performed RNA sequencing and f...

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Detalles Bibliográficos
Autores principales: Wörthmüller, Janine, Disler, Simona, Pradervand, Sylvain, Richard, François, Haerri, Lisa, Ruiz Buendía, Gustavo A., Fournier, Nadine, Desmedt, Christine, Rüegg, Curzio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417439/
https://www.ncbi.nlm.nih.gov/pubmed/37566008
http://dx.doi.org/10.3390/cells12151929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417439/
https://www.ncbi.nlm.nih.gov/pubmed/37566008
http://dx.doi.org/10.3390/cells12151929

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